3D Interaction Viewer and Database (3DIV) is an easy-to-use database providing epigenetic annotation, one-to-all chromatin interaction visualization in a variety of options. Spatial chromatin interaction has a significant role in gene regulation, and visualization and annotation of these interactions is key to connect between genetic/epigenetic variation and phenotypical polymorphism. For example, enhancer-promoter interaction is essential to regulate target gene expression. 3DIV provides following analysis; Interaction identification and annotation, interactive interaction visualization, and comparative interaction visualization
For more details, please click here.

Interaction Table
Interaction visualization
Comparative interaction visualization
Choose Sample(s)
  • Adrenal gland
  • Aorta
  • Bladder
  • Dorsolateral Prefrontal Cortex
  • Hippocampus
  • Lung
  • Liver
  • Left Ventricle
  • Ovary
  • Pancreas
  • Psoas
  • Right Ventricle
  • Small Bowel
  • Spleen
  • Thymus
  • H1 Embroynic Stem Cell
  • H1-derived Mesendoderm Cell
  • H1-derived Mesenchymal Stem Cell
  • H1-derived Neuronal Progenitor Cell
  • H1-derived Trophectoderm Cell
  • H9 Embryonic Stem Cell
  • H9-derived Neuro-Ectodermal Cell
  • GM12878 Lymphoblastoid Cell Line
  • IMR90 fibroblast, control
  • IMR90 fibroblast, flbopiridol treated
  • IMR90 fibroblast, TNF-α treated
  • Fibroblast(CRL-2522), control
  • Fibroblast(CRL-2522), dexamethasone 00h
  • Fibroblast(CRL-2522), dexamethasone 08h
  • Fibroblast(CRL-2522), dexamethasone 16h
  • Fibroblast(CRL-2522), dexamethasone 24h
  • Fibroblast(CRL-2522), dexamethasone 32h
  • Fibroblast(CRL-2522), dexamethasone 40h
  • Fibroblast(CRL-2522), dexamethasone 48h
  • Fibroblast(CRL-2522), dexamethasone 56h
  • Adenocarcinoma cell line(A549), dexamethasone 00h
  • Adenocarcinoma cell line(A549), dexamethasone 01h
  • Adenocarcinoma cell line(A549), dexamethasone 04h
  • Adenocarcinoma cell line(A549), dexamethasone 08h
  • Adenocarcinoma cell line(A549), dexamethasone 12h
  • LNCap prostate cancer cell line, BglII
  • PC3 prostate cancer cell line, BglII
  • PrEC normal Prostate epithelial cell, BglII
  • GM12878 dilution HiC, HindIII
  • GM12878 dilution HiC, NcoI
  • GM12878, in situ HiC, DpnII
  • GM12878, in situ HiC, NcoI
  • GM12878, in-situ MboI
  • HMEC, in-situ MboI
  • HUVEC, in-situ MboI
  • IMR90, in-situ MboI
  • K562, in-situ MboI
  • KBM7, in-situ MboI
  • NHEK, in-situ MboI
  • RWPE1 prostate epithelial cell line, ERG overexpression
  • RWPE1 prostate epithelial cell line, control
  • HEK293, TEV treated
  • HEK293, HRV treated
  • HEK293 siRNA Control
  • HEK293 siRNA CTCF
  • MCF-10A
  • MCF-7
  • MCF-10A, scramble shRNA
  • MCF-10A, BRG1 shRNA
  • MCF-7, non-specific shRNA
  • MCF-7, RUNX1 shRNA
  • A549 Cell Line
  • Caki2 Cell Line
  • G401 Cell Line
  • NCI-H460 Cell Line
  • LNCaP Cell Line
  • Panc1 Cell Line
  • RPMI-7951 Cell Line
  • SK-MEL-5 Cell Line
  • SK-N-DZ Cell Line
  • SK-N-MC Cell Line
  • T47D Cell Line
  • endothelial cell of hepatic sinusoid
  • astrocyte of the cerebellum
  • KBM7 cell line
More Experiment ▼
Bait :
(Ex. CROCCP2, chr22:27141000, rs42)
Items selected
No. Sample Bait
Interaction range
(Ex.chr22:26641000-27641000)

References

    3DIV: A 3D-genome Interaction Viewer and database
    Dongchan Yang, Insu Jang, Jinhyuk Choi, Min-Seo Kim, Andrew J Lee, Hyunwoong Kim, Junghyun Eom, Dongsup Kim, Inkyung Jung and Byungwook Lee
    Nucleic Acids Res. 2018 Jan; Vol 46, Issue D1 (Database issue):D52-57.
Gene symbols
loading
We highly recommend that you use the current version of Chrome and Safari browser for 3D-Genome Interaction Viewer & database
This system has been developed by KAIST and KOBIC